Polynucleotides are highly purified DNA molecules, which when injected, stimulate fibroblast activity and increase their numbers too. Fibroblasts are the cells responsible for the formation of connective tissue through their ability to produce collagen which helps maintain the skins firm structure. Additionally, they possess the ability to soothe inflammation and restore the balance of melanocyte activity (skin pigmentation), resulting in a more even and refreshed skin tone without adding volume like traditional dermal fillers. Polynucleotides have a unique role in skin rejuvenation and anti-ageing therapies. Their mechanism of action is multi-layered, involving several critical steps:
Collagen and Elastin Stimulation: They trigger the body’s production of collagen and elastin. Collagen provides structural support and firmness to the skin, while elastin contributes to its elasticity. The decline in these proteins due to ageing leads to wrinkles and skin laxity. Polynucleotides help reverse this by boosting the production of these essential proteins.
Improvement in Skin Hydration and Texture: Polynucleotides enhance the skin’s texture and hydration levels. This is achieved by improving the skin’s capacity to retain moisture, leading to a more hydrated and plump appearance.
Cellular Regeneration Promotion: They are effective in encouraging the repair and renewal of skin cells. This is particularly beneficial for skin damaged by environmental factors, helping to lessen the effects of ageing accelerated by external stressors.
Anti-inflammatory: The polynucleotides reduce inflammation in the skin and hence improve rosacea
Reduction in scarring: The polynucleotides can be used for acne scarring. The scars are first freed from the underlying tethering and the polynucleotides are then injected to improve the connective tissue and fill out the scars.
Polynucleotides are the new and revolutionary approach for:
Stimulation of collagen and elastin production- for an overall rejuvenation of the under eyes, face, neck and decolletage. Enhancing skin hydration, circulation and overall skin quality.
Eyes– Polynucleotides can reduce dark under-eye circle, smooth crow’s feet, fine lines, hollows and puffiness under the eyes.
Cheeks-Polynucleotides smooth folds and lines, tightening and lifting cheeks and hydrating skin.
Lines around the mouth– Polynucleotides smooth lines around the mouth/ smokers lines without plumping or adding volume.
Neck-Treats crepey and sagging skin.
Sun Damaged Skin -They help suppress melanocyte activity and therefore improve sun damage.
Cheeks-Polynucleotides smooth folds and lines, tightening and lifting cheeks and hydrating skin.
Lines around the mouth– Polynucleotides smooth lines around the mouth/ smokers lines without plumping or adding volume.
Neck-Treats crepey and sagging skin.
Sun Damaged Skin -They help suppress melanocyte activity and therefore improve sun damage.
Acne Scarring– Polynucleotides can be combined with subcision. The treatment helps to stimulate collagen to plump out areas with less volume
About The Treatment
Procedure Time
Numbing 30 Minutes in clinic then treatment time of 30 minutes
Recovery Time
Bruising or swelling can occur that may last for a few days
Anaesthetic
Numbing cream is applied for 30minutes prior to treatment
Back To Work
Same day if cannula used. Otherwise expect bumps on the skin for 2-3 days
Duration Of Results
6 months, after the initial course of treatment
No. Of Treatments
Course of 3 -4 treatments at 3 week intervals then maintenance treatment every 6 months
Pricing
| Treatment | Price |
|---|---|
| Single Session Face or Eyes | £300 |
| Single Session Face AND Eye | £600 |
| Course Eyes (3 sessions) | £825 |
| Course Face (3 sessions) | £825 |
| Course Face and Eyes (3 sessions) | £1500 |
| Maintenance Face and Eyes | £550 |
| Maintenance Eyes or Face | £275 |
| Neck | £300 |
| Decollete | £500 |
| Acne scarring Subcision and Polynucleotides | £400 per session |
What happens during the treatment?
The skin is cleaned and local anaesthetic cream is applied. After about 30 minutes, the skin is re- cleansed and the injections are administered with a very fine needle. Alternatively a blunt tip cannula is used whereby no local anaesthetic is required
The skin is cleaned and local anaesthetic cream is applied. After about 30 minutes, the skin is re- cleansed and the injections are administered with a very fine needle. Alternatively a blunt tip cannula is used whereby no local anaesthetic is required
Are there any side effects?
As with any injection, you can expect your skin to be slightly red and swollen immediately after the procedure. You may experience pin prick bruises and some redness, itching and a warm feeling in the skin.
As with any injection, you can expect your skin to be slightly red and swollen immediately after the procedure. You may experience pin prick bruises and some redness, itching and a warm feeling in the skin.
How many treatments are needed?
Depending on the skin condition severity, we normally advise 3 to 4 treatments spaced 3 weeks apart
Depending on the skin condition severity, we normally advise 3 to 4 treatments spaced 3 weeks apart
Can they be used alongside other treatments?
Yes, they can be used to “Prime” the skin prior to procedures eg microneedling, radiofrequency, dermal fillers and chemical peels to improve the results
Yes, they can be used to “Prime” the skin prior to procedures eg microneedling, radiofrequency, dermal fillers and chemical peels to improve the results
What are the expected results?
Initially there will be swelling giving a look of firmness to the skin that will last 2-4 days. It will then take fibroblasts take some time to activate and start producing collagen. Therefore, the best results are seen after about 3 months from starting your course of treatment. The skin will look firmer, smoother and more radiant.You will even notice a more even skin tone that looks younger and fresher. If you have had treatment with the product Newest, you can also expect the skin to be more hydrated and luminous. If you have had treatment with Plinest eye, the dark circles under the eyes will be reduced. After the initial course of treatment it is advisable to have 1 treatment every 6 months to maintain the skin fibroblast activity
Initially there will be swelling giving a look of firmness to the skin that will last 2-4 days. It will then take fibroblasts take some time to activate and start producing collagen. Therefore, the best results are seen after about 3 months from starting your course of treatment. The skin will look firmer, smoother and more radiant.You will even notice a more even skin tone that looks younger and fresher. If you have had treatment with the product Newest, you can also expect the skin to be more hydrated and luminous. If you have had treatment with Plinest eye, the dark circles under the eyes will be reduced. After the initial course of treatment it is advisable to have 1 treatment every 6 months to maintain the skin fibroblast activity